This scholarship has been extracted from the BEST GRANTS WEB: Grant 2016 - 2016 =)
Postdoctoral position in Disease Systems Biology – Computational analysis of data from embryonal tumours
Title: Postdoc, Department of Disease Systems Biology
Tenure: Two years, with potential extension for additional one year
Employment conditions:
Employment will be in accordance with the provisions of the collective agreement between the Danish Government and AC (the Danish Confederation of Professional Associations). The position will be at the level of postdoctoral fellow. To the basic salary, a monthly contribution to a pension fund is added (17.1% of the salary), and a supplement could be negotiated, dependent on the candidate´s experience and qualifications. In all cases, ability to perform the job will be the primary consideration, and thus we encourage all – regardless of their personal background and status – to apply.
Background:
The Novo Nordisk Foundation Center for Protein Research (CPR) has been established at the Faculty of Health Sciences, University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance. The Center comprises a wide range of expertise and resources, from in silico target identification, proteomics, high throughput protein production and characterisation to chemical biology, disease mechanisms and protein therapeutics. To date, more than 100 scientists have been recruited (out of an expected ~150). We are now seeking a postdoctoral fellow to the Department of Disease Systems Biology.
The Department of Disease Systems Biology headed by Prof. Søren Brunak works on disease-related integrative biology, in close contact with the other research groups at the Center, and focuses on a number of projects, including kinome-wide understanding of signal transduction networks; impact of human variation on signal transduction (germline and somatic); network association between diseases, genes, proteins and chemical compounds and disease-related text mining of electronic patient records, biobank data and biomedical literature.
Job description:
The ideal candidate should be able to conduct independent and creative research within systems biology, demonstrate scientific productivity, and show good interpersonal and communication skills. The postdoctoral fellow will be involved in the ongoing research projects in the department and will play a key role in the department´s obligation in the EU FP7 research project, ASSET: Analyzing and Striking the Sensitivities of Embryonal Tumours. ASSET operates a systems biology-driven discovery and validation engine to achieve the following objectives:
network analysis of time-resolved phosphoproteomics data from embryonic tumor tyrosine kinase activated cell lines in collaboration with the Department of Proteomics at CPR,
the combined analysis of genomic mutations, transcriptome, miRNA expression and dynamic proteome changes,
systematic perturbations to probe and refine these networks,
implementation of a virtuous cycle of model making and validation in relevant biological model systems (cell culture models and preclinical mouse models) and clinical samples.
In ASSET the department will use its experience of large scale data management and systems biology oriented data integration. A piloting of multiplexed targeted sequencing is a unique contribution to the project and will be valuable to ASSET for cost effective exon sequencing in embryonic tumours. The candidate will be involved in interpretation of massive amounts of genomics and proteomics data, design of a datawarehouse and the construction of computational pipelines for data integration and managed curation. The postdoctoral candidate is expected to contribute significantly to this research effort.
Qualifications:
The candidate is required to have a PhD or equivalent degree in natural or medical science.
Excellent scientific track record.
Prior experience in computational biology, data curation and data interpretation is highly desired.
Knowledge in genetics and biology, cell signaling, cancer systems biology and/or embryonal diseases would be considered a distinct advantage.
Good communication skills, both oral and written.
An analytical attitude of devising innovative scientific or technical solutions.
Demonstrate enthusiasm, motivation, flexibility and confidence.
For further information, please contact Professor Søren Brunak (soren.brunak@cpr.ku.dk)
Your application marked “211-0079/11-3850 ASSET- Postdoctoral position CPR_DSB, Professor Søren Brunak” including a CV as well as names and contact details of two referees must be sent to the Novo Nordisk Foundation Center for Protein Research before 10 February 2011by e-mail to jobs@cpr.ku.dk
All the complete information in Postdoctoral position in Disease Systems Biology !