This scholarship has been extracted from the BEST GRANTS WEB: Grant 2016 - 2016 =)
MicroRNA regulation of the host response to bovine tuberculosis.
A four-year PhD studentship utilising transcriptomics (RNA-seq) and systems biology approaches to investigate microRNA regulation of the host response to bovine tuberculosis is available. This is a collaborative project between researchers at the Smurfit Institute of Genetics, Trinity College Dublin; the Animal Genomics Laboratory, University College Dublin; and the Animal & Bioscience Research Department, Teagasc (Irish Agriculture and Food Development Authority). Applicants should have a 2.1 honours degree or higher in one of the following disciplines: Genetics/Genomics, Immunology, Microbiology, Cell Biology or Biochemistry. Experience in Bioinformatics/Computational Biology would be an asset.
Tuberculosis is a devastating disease of humans and animals. Bovine tuberculosis, caused by Mycobacterium bovis, is a major zoonotic pathogen and causes losses to global agriculture of approx. ?2.2 billion per annum. In order to develop strategies to control tuberculosis, we need to understand how the pathogen causes disease and can subvert the host immune response. MicroRNAs are post-tramics (RNA-seq) to profile microRNA expression in the early host response to M. bovis in bovine macrophages and will utilise systems biology approaches to investigate the regulatory networks involved in this response. The project will involve both lab-based experimental approaches and computational analysis.
The successful applicant will be registered as a PhD student at Trinity College Dublin (Prof. Dan Bradley’s Lab. http://www.gen.tcd.ie/molpopgen/) and will interact closely with Prof. David MacHugh’s lab at University College Dublin (http://animalgenomics.ucd.ie/), where the infection studies will be undertaken. The student will be primarily based in Dr. David Lynn’s Lab at the Teagasc Animal & Bioscience Research Department, which is located just outside Dublin in Co. Meath. The Teagasc Animal & Bioscience Research Department is a major new initiative to expand Teagasc’s capacity for advanced research in animal bioscience. Dr. Lynn has significant international experience in utilising systems biology approaches to investigate the host response to human pathogens and has recently established his lab at Teagasc. There are currently 3 other graduate students in the lab. http://www.agresearch.teagasc.ie/animalbioscience/people/dlynn.asp
This Teagasc Walsh Fellowship Award is ?21,000/year for 4 years. TCD postgraduate fees must be paid from this with the balance available as a student stipend (?15,000).
Applications (CV, cover letter and contact details for two referees) in Word or PDF format should be emailed to Dr. David Lynn, Animal & Bioscience Research Department, Teagasc (Irish Agriculture and Food Development Authority), Grange, Dunsany, Co. Meath, Ireland. david.lynn@teagasc.ie
Unfortunately, funding for postgraduate fees is only available to pay EU student fees. Non-EU students would be liable for the balance of fees payable for international students.
Teagasc/Trinity College Dublin
Animal & Bioscience/Genetics?- Dublin/Meath
IRELAND
email?david.lynn@teagasc.ie
Application Deadline 31/08/2010
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